Date: Tuesday, 21 October 2025
Kick-off: 18:45 BST (16:45 UTC)
Venue: Estadi Olímpic Lluís Companys, Barcelona

European nights are back, and this one’s got a nice bit of nostalgia about it. Barcelona welcome Olympiacos to the Estadi Olímpic, and it’s got that “big night under the lights” feel. The last time these two met, Messi was still pulling strings, and Olympiacos somehow kept a clean sheet. Feels like ages ago, right?

This time, things look a little different. Barcelona are rebuilding under Hansi Flick, while Olympiacos are still trying to prove they belong with the continent’s big boys. So, can the Greeks cause an upset in Catalonia? Let’s dive in.

Barcelona Team News

Flick must be tearing his hair out with this injury list. Seriously, it’s long enough to fill a bench. Ter Stegen, Raphinha, Lamine Yamal, and Dani Olmo are all out. That’s a lot of creativity gone.

Still, Barcelona aren’t short on firepower. Robert Lewandowski leads the line, and Marcus Rashford has settled in nicely since joining in the summer. Pedri looks fit and firing again — and that’s huge. When he’s on the ball, the whole team just breathes.

You’ll probably see Iñaki Peña start in goal again, with Araujo and Cubarsí marshalling the defence. Frenkie de Jong and Marc Casadó should sit deep, allowing Pedri to do his thing higher up. Rashford and Roony Bardghji are expected to buzz around Ferran Torres up top. It’s not quite the lineup Flick imagined when he arrived, but it’s still got quality everywhere.

Olympiacos Team News

Now, Olympiacos — they’ve had a rocky start to the season. Their form’s been all over the place, and they’re coming off a 2-1 defeat to PAOK. That’s not ideal prep for a trip to Barcelona.

The good news? They’ve got a clean bill of health — no injuries, no suspensions. José Mendilibar has his full squad to pick from. The bad news? They’ll probably spend most of this match defending.

Expect a tight 4-4-2 setup, with Daniel Podence working his socks off on the left and Ayoub El Kaabi leading the line. El Kaabi’s the one to watch — he’s quick, strong, and knows how to find space behind defenders. The problem? He won’t get much service.

Barcelona vs Olympiacos Head-to-Head

You won’t believe this, but these two haven’t met since 2017. Back then, Olympiacos somehow held Barcelona to a 0-0 draw in Greece. But in Spain? Different story. Barça ran out 3-1 winners that night — and that was when they were down to ten men.

Overall, it’s not even close. Barcelona have dominated this matchup every time. Olympiacos might keep it tight for a while, but it’s hard to see them holding out for 90 minutes at the Camp Nou’s temporary home.

Form Check

Barcelona’s form has been a bit mixed. Three wins in their last five, but two painful losses — including that 4-1 hammering at Sevilla. Defensively, they’ve looked shaky, conceding nine goals in their last six games. That’s not Flick football.

Olympiacos aren’t exactly flying either. Two wins in six, and those came against mid-table Greek sides. In Europe, they’ve looked off the pace — goalless against Pafos, beaten comfortably by Arsenal. You can see where this is going.

Barcelona vs Olympiacos Betting Tips

Alright, let’s talk money. Here’s what I think — Barcelona win, and they score at least twice. The odds on Barcelona to win & over 2.5 goals are solid, and that’s probably the safest bet of the night.

If you’re chasing a bit more, Lewandowski to score anytime is a banker. He loves these games — and he’s due a goal after a quiet couple of weeks. You could also look at Both Teams to Score (Yes) if you fancy Olympiacos nicking one on the break. Flick’s high line always leaves space, and El Kaabi only needs one chance.

Barcelona vs Olympiacos Prediction

So, here’s how I see it going. Barcelona dominate the ball, keep Olympiacos pinned in their own half, and slowly wear them down. It might not be fireworks early on, but the chances will come.

Olympiacos will defend deep, maybe even nick a goal on the counter, but it’s hard to imagine them holding out once Barça find their rhythm. Expect the home crowd to roar them on after the disappointment against PSG and Sevilla.

Match Prediction: Barcelona to win. Bet with bet365.

Barcelona vs Olympiacos Correct Score Tip

If you like your scorelines tidy, Barcelona 3-1 Olympiacos feels about right. Barcelona’s defence leaks one, but their attack does the rest.

Correct Score Prediction: Barcelona 3–1 Olympiacos. Bet with bet365.

Barcelona vs Olympiacos Over/Under Goals Tip

Looking at both sides’ recent games, goals seem guaranteed. Barcelona’s last six matches have all gone over 2.5, and Olympiacos haven’t kept a clean sheet in their last five away games.

Tip: Over 3.5 goals.
Because honestly, neither team can defend right now.

Over/Under Prediction: Over 3.5 Goals. Bet with bet365.

Barcelona vs Olympiacos Bet Builder Idea

If you like a combo bet, here’s one worth a shot:

• Barcelona to win
• Both teams to score
• Lewandowski anytime scorer

That’s your “Champions League night special.” Plenty of action, goals, and a likely home win.

Bet Builder Tip: Barcelona to Win, BTTS Yes, Lewandowski anytime Anytime Scorer. Bet with bet365.

Key Stats

• Barcelona have scored 10 goals in their last four home matches.
• Olympiacos have lost 3 of their last 4 away games in Europe.
• Barcelona have conceded in five of their last six matches.
• Olympiacos haven’t beaten a Spanish side away since 1999.

Visit our football previews & predictions page for more betting tips on upcoming matches.

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